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TC-A-2317 HCl

目录号: A13567
Aurora kinase A 抑制剂
TC-A-2317 盐酸盐是一种强效的Aurora kinase A抑制剂(Ki = 1.2 nM,相比之下对Aurora kinase B的抑制为101 nM)。相较于其他60种激酶具有选择性(IC50值 > 1000 nM)。具有良好的细胞渗透性和抗肿瘤活性。
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规格 价格 库存 数量
5mg
¥1,680.00
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10mg
¥3,220.00
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25mg
¥6,440.00
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50mg
¥11,760.00
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生物活性
Discription TC-A-2317 hydrochloride is a potent Aurora kinase A inhibitor (Ki = 1.2 nM compared to 101 nM for inhibition of Aurora kinase B). Selective over 60 other kinases (IC50 values > 1000 nM). Exhibits good cell permeability and antitumor activity.
产品信息
目录号 A13567
分子式 C19H28N6O.HCl
分子量 392.93
CAS号 1245907-03-2
SMILES CC(CCCC(C)(C)O)NC1=NC(NC2=NNC(C)=C2)=CC(C)=C1[N+]#[C-].Cl
其他名称 TCA2317
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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