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TC-E 5006

Gamma-secretase modulator

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产品目录号: A13217


产品名 目录号 价格 数量
TC-E 5006 5mg A13217-5
¥ 1,400.00
TC-E 5006 10mg A13217-10
¥ 2,200.00
TC-E 5006 50mg A13217-50
¥ 9,800.00



TC-E 5006 is a gamma-secretase modulator. Reduces Aβ42 levels in vitro (EC50 = 390 nM) and in vivo.

TC-E 5006




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Chemical Information

目录号 A13217
Mechanism of action Modulator
分子量 499.54
化学分子式 C29H29F4NO2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1257395-14-4
Synonyms TC-E5006, TC-E-5006
SMILES code CC1CCN(CC1)C(C2=CC=C(C=C2)F)C3=C(C=C(C=C3)C(C)C(=O)O)C4=CC=C(C=C4)C(F)(F)F
化学名称 2-[4-[(4-fluorophenyl)-(4-methylpiperidin-1-yl)methyl]-3-[4-(trifluoromethyl)phenyl]phenyl]propanoic acid


TC-E 5006 is a gamma-secretase modulator. Reduces Aβ42 levels in vitro (EC50 = 390 nM) and in vivo.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.02 mL 100.09 mL 200.18mL
0.5 mM 4 mL 20.02 mL 40.04 mL
1 mM 2 mL 10.01 mL 20.02 mL
5 mM 0.4 mL 2 mL 4 mL

*The above data is based on the productmolecular weight 499.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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