TCS 21311

目录号: A15365

JAK3 抑制剂

TCS 21311 Chemical Structure

CAS NO. 1260181-14-3

TCS 21311 is a potent JAK3 inhibitor (IC50 = 8 nM). TCS 21311 is selective for JAK3 over JAK1, JAK2 and Tyk 2 (IC50 values are 1017, 2550 and 8055 nM respectively).

库存: 现货

规格 价格 数量
10 mg
¥ 1,900.00
50 mg
¥ 7,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

TCS 21311 is a potent JAK3 inhibitor (IC50 = 8 nM). TCS 21311 is selective for JAK3 over JAK1, JAK2 and Tyk 2 (IC50 values are 1017, 2550 and 8055 nM respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.99 mL 94.96 mL 189.93 mL
0.5 mM 3.8 mL 18.99 mL 37.99 mL
1 mM 1.9 mL 9.5 mL 18.99 mL
5 mM 0.38 mL 1.9 mL 3.8 mL

*The above data is based on the productmolecular weight 526.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15365
MECHANISM OF ACTION Inhibitor
M. Wt 526.51
Formula C27H25F3N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1260181-14-3
Synonyms TCS21311, TCS-21311
SMILES CC(C)(C(=O)N1CCN(CC1)C2=CC(=C(C=C2)C(F)(F)F)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54)O

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