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TCS 401是蛋白酪氨酸磷酸酶1B（PTP1B）的选择性抑制剂（对于PTP1B，CD45 D1D2，PTPβ，PTPεD1，SHP-1，Ki值为0.29、59、560、1100，> 2000，> 2000和> 2000μM，分别为PTPαD1和LAR D1D2）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37 mL | 185.01 mL | 370.01 mL |
| 0.5 mM | 7.4 mL | 37 mL | 74 mL |
| 1 mM | 3.7 mL | 18.5 mL | 37 mL |
| 5 mM | 0.74 mL | 3.7 mL | 7.4 mL |
*The above data is based on the productmolecular weight 270.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15390 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 270.26 |
| Formula | C10H10N2O5S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 243967-42-2 |
| Synonyms | TCS401, TCS-401 |
| SMILES | O=C(C1=C(NC(C(O)=O)=O)SC2=C1CCNC2)O |
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