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TD-0212

TD-0212

Name: TD-0212
SKU: A13715

目录号: A13715

neprilysin (NEP) inhibitor

TD-0212 Chemical Structure

CAS NO. 1073549-10-6

TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP.

库存：现货

规格	价格	数量
1 mg	￥ 3,600.00
5 mg	￥ 10,800.00
10 mg	￥ 18,400.00
50 mg	￥ 55,200.00

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生物活性

TD-0212 (compound 35) is an orally active dual pharmacology angiotensin II type 1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, with a pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.95 mL	94.76 mL	189.52 mL
0.5 mM	3.79 mL	18.95 mL	37.9 mL
1 mM	1.9 mL	9.48 mL	18.95 mL
5 mM	0.38 mL	1.9 mL	3.79 mL

*The above data is based on the productmolecular weight 527.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13715
作用机制	Inhibitor (抑制剂)
M. Wt	527.65
Formula	C28H34FN3O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1073549-10-6
Synonyms	TD0212, TD-0212
SMILES	OC(C1=CC=CC=C1C2=CC=C(CN3C(CNC([C@H](CC(C)C)S)=O)=C(CC)N=C3OCC)C(F)=C2)=O