Tefinostat

目录号: A20258

pan HDAC inhibitor

Tefinostat

Tefinostat Chemical Structure

CAS NO. 914382-60-8

Tefinostat (CHR-2845) is a monocyte/macrophage-targeted pan HDAC inhibitor, cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Anti-monocytoid lineage leukaemias activity.

库存: 现货

规格 价格 数量
5 mg
¥ 3,150.00
10 mg
¥ 5,430.00
50 mg
¥ 16,100.00
100 mg
¥ 32,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Tefinostat (CHR-2845) is a monocyte/macrophage-targeted pan HDAC inhibitor, cleaved into active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1). Anti-monocytoid lineage leukaemias activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.18 mL 100.89 mL 201.77 mL
0.5 mM 4.04 mL 20.18 mL 40.35 mL
1 mM 2.02 mL 10.09 mL 20.18 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 495.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A20258
M. Wt 495.61
Formula C28H37N3O5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 914382-60-8
Synonyms CHR-2845, CHR2845, CHR 2845
SMILES O=C(OC1CCCC1)[C@H](C2=CC=CC=C2)NCC3=CC=C(NC(CCCCCCC(NO)=O)=O)C=C3

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