Tegoprazan
目录号: A20873
gastric H+/K+-ATPase 抑制剂
Tegoprazan,一种钾竞争性酸阻断剂,是一种强效的、口服活性的、高度选择性的胃H+/K+-ATPase抑制剂,能够控制胃酸分泌和胃动力,其 IC50 值在 0.29-0.52 μM 范围内,适用于体外的猪、犬和人类H+/K+-ATPases。
Discription | Tegoprazan, a potassium-competitive acid blocker, is a potent, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro. |
---|
目录号 | A20873 |
---|---|
分子式 | C20H19F2N3O3 |
分子量 | 387.38 |
CAS号 | 942195-55-3 |
SMILES | FC1=CC(F)=C2[C@@H](OC3=CC(C(N(C)C)=O)=CC4=C3N=C(C)N4)CCOC2=C1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2