Tegoprubart is a monoclonal antibody specifically targeting the CD40 ligand (CD40L), an essential component of immune system costimulation. By inhibiting CD40L, Tegoprubart effectively diminishes both cellular and antibody-mediated immune responses, facilitating the creation of a more tolerant immune environment. This antibody has demonstrated significant in vivo efficacy in various transplantation animal models, underscoring its potential utility in immune modulation and transplant medicine.
Tegoprubart is a monoclonal antibody specifically targeting the CD40 ligand (CD40L), an essential component of immune system costimulation. By inhibiting CD40L, Tegoprubart effectively diminishes both cellular and antibody-mediated immune responses, facilitating the creation of a more tolerant immune environment. This antibody has demonstrated significant in vivo efficacy in various transplantation animal models, underscoring its potential utility in immune modulation and transplant medicine.
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