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Telaprevir (VX-950)


HCV NS3-4A protease 抑制剂

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产品目录号: A10902


产品名 目录号 价格 数量
Telaprevir (VX-950) 2mg A10902-2
¥ 600.00
Telaprevir (VX-950) 5mg A10902-5
¥ 900.00
Telaprevir (VX-950) 10mg A10902-10
¥ 1,600.00
Telaprevir (VX-950) 25mg A10902-25
¥ 3,200.00
Telaprevir (VX-950) 10mM * 1mL in DMSO A10902-10mM-D
¥ 1,800.00



Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.

Telaprevir (VX-950)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Telaprevir (VX-950) 发表的文献 (3)
  • Jacobs CL, .et al. StaPLs: versatile genetically encoded modules for engineering drug-inducible proteins, Nat Methods, 2018, Jul;15(7):523-526 PMID: 29967496
  • Apriyanto DR, .et al. Anti-Hepatitis C Virus Activity of a Crude Extract from Longan (Dimocarpus longan Lour.) Leaves, Jpn J Infect Dis, 2016, May 20;69(3):213-20 PMID: 26255732
  • Mizuki Yamamoto, .et al. Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay, Antimicrob Agents Chemother, 2016, Nov; 60(11): 6532每6539 PMID: 27550352

Chemical Information

目录号 A10902
Mechanism of action Inhibitor
分子量 679.9
化学分子式 C36H53N7O6
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 402957-28-2
Synonyms VX950, Incivek, Incivo
SMILES code CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5
化学名称 (1S,3aR,6aS)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-1-carboxamide


Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.
HCV NS3-4A serine protease
0.35 μM


Solubility (25°C) * In vitro DMSO 136 mg/mL (200.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.71 mL 73.54 mL 147.08mL
0.5 mM 2.94 mL 14.71 mL 29.42 mL
1 mM 1.47 mL 7.35 mL 14.71 mL
5 mM 0.29 mL 1.47 mL 2.94 mL

*The above data is based on the productmolecular weight 679.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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