Telatinib (BAY 57-9352)
目录号: A10903
VEGFR-2 抑制剂
Telatinib(BAY 57-9352)是一种口服的小分子抑制剂,针对血管内皮生长因子受体2和3(VEGFR-2/-3)以及血小板源生长因子受体β酪氨酸激酶进行抑制。
Discription | Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases. | ||
---|---|---|---|
Targets |
|
目录号 | A10903 |
---|---|
分子式 | C20H16ClN5O3 |
分子量 | 409.8 |
CAS号 | 332012-40-5 |
SMILES | CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl |
其他名称 | BAY57-9352 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 71 mg/mL (173.24 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL (2.44 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.4 mL | 122.01 mL | 244.02 mL |
0.5 mM | 4.88 mL | 24.4 mL | 48.8 mL |
1 mM | 2.44 mL | 12.2 mL | 24.4 mL |
5 mM | 0.49 mL | 2.44 mL | 4.88 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2