Telatinib (BAY 57-9352)

目录号: A10903

VEGFR-2 inhibitor

Telatinib (BAY 57-9352) Chemical Structure

CAS NO. 332012-40-5

Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,500.00
100 mg
¥ 7,500.00
10mM * 1mL in DMSO
¥ 1,330.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases.
Targets
c-Kit VEGFR3 VEGFR2 PDGFRα
1 nM4 nM6 nM15 nM
In vitro DMSO 82 mg/mL (200.08 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (2.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.4 mL 122.01 mL 244.02 mL
0.5 mM 4.88 mL 24.4 mL 48.8 mL
1 mM 2.44 mL 12.2 mL 24.4 mL
5 mM 0.49 mL 2.44 mL 4.88 mL

*The above data is based on the productmolecular weight 409.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10903
MECHANISM OF ACTION Inhibitor
M. Wt 409.8
Formula C20H16ClN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 332012-40-5
Synonyms BAY57-9352
SMILES CNC(=O)C1=NC=CC(=C1)COC2=NN=C(C3=C2OC=C3)NC4=CC=C(C=C4)Cl

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