Tenalisib (RP6530)

Name: Tenalisib (RP6530)
SKU: A16799
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A16799

dual PI3Kδ/γ 抑制剂

Tenalisib（也称为RP6530）是一种强效且选择性的双重PI3Kδ/γ抑制剂，它能抑制B细胞淋巴瘤细胞系的生长，并伴随下游生物标志物pAKT的减少。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥455.00	现货
10mg	¥735.00	现货
25mg	¥1,330.00	现货
50mg	¥2,205.00	现货
100mg	¥3,325.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Tenalisib, also known as RP6530, is a potent and selective dual PI3Kδ/γ inhibitor that inhibited growth of B-cell lymphoma cell lines with a concomitant reduction in the downstream biomarker, pAKT.

Targets

Target	Value

产品信息

目录号	A16799
分子式	C23H18FN5O2
分子量	415.43
CAS号	1639417-53-0
SMILES	O=C1C(C2=CC=CC(F)=C2)=C([C@@H](NC3=C4NC=NC4=NC=N3)CC)OC5=C1C=CC=C5
其他名称	RP-6530, RP 6530
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	74 mg/mL (178.13 mM)
	Water	Insoluble
	Ethanol	74 mg/mL (178.13 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.07 mL	120.36 mL	240.71 mL
0.5 mM	4.81 mL	24.07 mL	48.14 mL
1 mM	2.41 mL	12.04 mL	24.07 mL
5 mM	0.48 mL	2.41 mL	4.81 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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