Tenatumomab (ST2146) is a murine monoclonal antibody developed to target tenascin-C, a large extracellular glycoprotein frequently overexpressed in various cancers. This antibody has demonstrated utility in advanced diagnostic and therapeutic techniques, including Pretargeted Antibody Guided Radioimmunotherapy (PAGRIT). Through PAGRIT, as well as direct labeling with 131-Iodine, tenatumomab facilitates the precise delivery of radionuclides to tumor sites, enhancing the specificity and efficacy of cancer imaging and treatment modalities.
Tenatumomab (ST2146) is a murine monoclonal antibody developed to target tenascin-C, a large extracellular glycoprotein frequently overexpressed in various cancers. This antibody has demonstrated utility in advanced diagnostic and therapeutic techniques, including Pretargeted Antibody Guided Radioimmunotherapy (PAGRIT). Through PAGRIT, as well as direct labeling with 131-Iodine, tenatumomab facilitates the precise delivery of radionuclides to tumor sites, enhancing the specificity and efficacy of cancer imaging and treatment modalities.
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