Tenovin-1
目录号: A11943
p53 activator
Tenovin-1 是一种小分子激活剂,能够激活 p53 的转录活性,保护 p53 免受 MDM2 介导的降解。
| Discription | Tenovin-1 is a small molecule activator of p53 transcriptional activity that protects against MDM2-mediated p53 degradation. | ||
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| Targets |
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| 目录号 | A11943 |
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| 分子式 | C20H23N3O2S |
| 分子量 | 369.5 |
| CAS号 | 380315-80-0 |
| SMILES | CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 65 mg/mL (175.92 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 15% Captisol | 14 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.06 mL | 135.32 mL | 270.64 mL |
| 0.5 mM | 5.41 mL | 27.06 mL | 54.13 mL |
| 1 mM | 2.71 mL | 13.53 mL | 27.06 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2