TEPP-46

目录号: A16279

PKM2 activator

TEPP-46

TEPP-46 Chemical Structure

CAS NO. 1221186-53-3

TEPP-46 is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2) with half-maximum activating concentration (AC50 value) of 92 nM, and little or no activity versus PKM1, PKL and PKR.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
50 mg
¥ 4,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

TEPP-46 is a potent and selective activator of recombinant pyruvate kinase M2 (PKM2) with half-maximum activating concentration (AC50 value) of 92 nM, and little or no activity versus PKM1, PKL and PKR.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.85 mL 134.24 mL 268.49 mL
0.5 mM 5.37 mL 26.85 mL 53.7 mL
1 mM 2.68 mL 13.42 mL 26.85 mL
5 mM 0.54 mL 2.68 mL 5.37 mL

*The above data is based on the productmolecular weight 372.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A16279
MECHANISM OF ACTION Activator
M. Wt 372.46
Formula C17H16N4O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1221186-53-3
Synonyms ML-265
SMILES O=C1C(N(C)C2=C3SC(S(C)=O)=C2)=C3C=NN1CC4=CC=CC(N)=C4

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