Teriflunomide
目录号: A18052
Teriflunomide 是 Leflunomide 的活性代谢物,是一种经批准用于治疗类风湿性关节炎的疗法。它抑制嘧啶合成,因此强效地减少了 T细胞 和 B细胞 的增殖。
Discription | Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation. | |||||
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Cell Research |
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目录号 | A18052 |
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分子式 | C12H9F3N2O2 |
分子量 | 270.21 |
CAS号 | 163451-81-8 |
SMILES | C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O.[(Z)] |
其他名称 | A77 1726, A77-1726 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 28 mg/mL (103.62 mM) | |
Water | Insoluble | ||
Ethanol | <1 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 37.01 mL | 185.04 mL | 370.08 mL |
0.5 mM | 7.4 mL | 37.01 mL | 74.02 mL |
1 mM | 3.7 mL | 18.5 mL | 37.01 mL |
5 mM | 0.74 mL | 3.7 mL | 7.4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2