Tesidolumab (LFG316) is a fully human IgG1/?? monoclonal antibody with a molecular weight of 143 kDa in its non-glycosylated form. This antibody specifically targets and binds to complement component 5 (C5), effectively inhibiting its cleavage and the subsequent formation of the membrane attack complex (MAC). This blockade is crucial in preventing the cascade of events that lead to cell lysis and inflammation, making Tesidolumab a valuable tool for research into complement-mediated diseases and therapeutic interventions.
Tesidolumab (LFG316) is a fully human IgG1/?? monoclonal antibody with a molecular weight of 143 kDa in its non-glycosylated form. This antibody specifically targets and binds to complement component 5 (C5), effectively inhibiting its cleavage and the subsequent formation of the membrane attack complex (MAC). This blockade is crucial in preventing the cascade of events that lead to cell lysis and inflammation, making Tesidolumab a valuable tool for research into complement-mediated diseases and therapeutic interventions.
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