Tetrandrine (Fanchinine)
目录号: A10921
Calcium Channel 抑制剂
Tetrandrine 是一种钙通道阻断剂。它抑制肥大细胞的脱颗粒作用。Tetrandrine 具有抗炎和抗纤维化作用,这使得 tetrandrine 及其相关化合物在治疗肺硅沉着病、肝硬化和类风湿性关节炎方面具有潜在的应用价值。
| Discription | Tetrandrine is a calcium channel blocker. It inhibits the degranulation of mast cells.Tetrandrine has anti-inflammatory and anti-fibrogenic actions, which make tetrandrine and related compounds potentially useful in the treatment of lung silicosis, liver cirrhosis, and rheumatoid arthritis. | |||||
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| Cell Research |
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| 目录号 | A10921 |
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| 分子式 | C38H42N2O6 |
| 分子量 | 622.8 |
| CAS号 | 518-34-3 |
| SMILES | CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC |
| 其他名称 | Fanchinine, Hanfangchin A, NSC 77037, S,S-(+)-Tetrandrine, Sinomenine A, TTD, Tetrandrin, d-Tetrandr |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | Warmed: 1 mg/mL (1.6 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (3.21 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.06 mL | 80.28 mL | 160.57 mL |
| 0.5 mM | 3.21 mL | 16.06 mL | 32.11 mL |
| 1 mM | 1.61 mL | 8.03 mL | 16.06 mL |
| 5 mM | 0.32 mL | 1.61 mL | 3.21 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2