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PI3K 抑制剂

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产品目录号: A10922


产品名 目录号 价格 数量
TG100-115 5mg A10922-5
¥ 600.00
TG100-115 10mg A10922-10
¥ 1,000.00
TG100-115 25mg A10922-25
¥ 1,900.00
TG100-115 100mg A10922-100
¥ 5,500.00
TG100-115 10mM * 1mL in DMSO A10922-10mM-D
¥ 1,010.00



TG100-115 inhibits PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively).





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Chemical Information

目录号 A10922
Mechanism of action Inhibitor
分子量 346.3
化学分子式 C18H14N6O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 677297-51-7
Synonyms TG100115
SMILES code C1=CC(=CC(=C1)O)C2=NC3=C(N=C2C4=CC(=CC=C4)O)N=C(N=C3N)N
化学名称 3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol (6,7-Bis(3-hydroxyphenyl)pteridine-2,4-diamine)


TG100-115 inhibits PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively).
83 nM235 nM1.2 μM1.3 μM


Solubility (25°C)* In vitro DMSO 9 mg/mL (25.98 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.88 mL 144.38 mL 288.77mL
0.5 mM 5.78 mL 28.88 mL 57.75 mL
1 mM 2.89 mL 14.44 mL 28.88 mL
5 mM 0.58 mL 2.89 mL 5.78 mL

*The above data is based on the productmolecular weight 346.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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