TG100-115
目录号: A10922
PI3K 抑制剂
TG100-115 抑制 PI3K γ 和 -δ（分别的 IC50 值为 83 和 235 nM）。
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生物活性
| Discription | TG100-115 inhibits PI3K γ and -δ(IC50 values of 83 and 235 nM, respectively). | ||
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| Targets |
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产品信息
| 目录号 | A10922 |
|---|---|
| 分子式 | C18H14N6O2 |
| 分子量 | 346.3 |
| CAS号 | 677297-51-7 |
| SMILES | C1=CC(=CC(=C1)O)C2=NC3=C(N=C2C4=CC(=CC=C4)O)N=C(N=C3N)N |
| 其他名称 | TG100115 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 8 mg/mL (23.09 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+30% PEG 300+ddH2O | 0.3 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.88 mL | 144.38 mL | 288.77 mL |
| 0.5 mM | 5.78 mL | 28.88 mL | 57.75 mL |
| 1 mM | 2.89 mL | 14.44 mL | 28.88 mL |
| 5 mM | 0.58 mL | 2.89 mL | 5.78 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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