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TGR-1202 hydrochloride

PI3K?? 抑制剂

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产品目录号: A16278

库存状态:中国现货中国现货

产品名 目录号 价格 数量
TGR-1202 hydrochloride 5mg A16278-5
¥ 1,200.00
TGR-1202 hydrochloride 10mg A16278-10
¥ 2,200.00
TGR-1202 hydrochloride 50mg A16278-50
¥ 5,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

TGR-1202 hydrochloride is an orally available, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 and 24.3 nM respectively.

TGR-1202 hydrochloride

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Chemical Information

目录号 A16278
Mechanism of action Inhibitor
分子量 608.01
化学分子式 C31H25ClF3N5O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1532533-78-0
Synonyms RP5264 hydrochloride, TGR1202 hydrochloride, TGR 1202 hydrochloride, RP-5264 hydrochloride, RP 5264 hydrochloride
SMILES code O=C1C(C2=CC=CC(F)=C2)=C([C@@H](N3N=C(C4=CC=C(OC(C)C)C(F)=C4)C5=C(N)N=CN=C53)C)OC6=CC=C(F)C=C16.[H]Cl
化学名称 (S)-2-(1-(4-amino-3-(3-fluoro-4-isopropoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-6-fluoro-3-(3-fluorophenyl)-4H-chromen-4-one hydrochloride

生物活性

Description
TGR-1202 hydrochloride is an orally available, next generation PI3Kδ inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 and 24.3 nM respectively.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.45 mL 82.24 mL 164.47mL
0.5 mM 3.29 mL 16.45 mL 32.89 mL
1 mM 1.64 mL 8.22 mL 16.45 mL
5 mM 0.33 mL 1.64 mL 3.29 mL

*The above data is based on the productmolecular weight 608.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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