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TH1020 is a potent and selective toll-like receptor 5 (TLR5)/flagellin complex antagonist with an IC50 of 0.85 μM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.05 mL | 110.24 mL | 220.49 mL |
| 0.5 mM | 4.41 mL | 22.05 mL | 44.1 mL |
| 1 mM | 2.2 mL | 11.02 mL | 22.05 mL |
| 5 mM | 0.44 mL | 2.2 mL | 4.41 mL |
*The above data is based on the productmolecular weight 453.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22703 |
|---|---|
| M. Wt | 453.54 |
| Formula | C23H15N7S2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 1841460-82-9 |
| Synonyms | TH 1020,TH-1020 |
| SMILES | C12=NC=NC(SC3=NN=C(N3CC4=CC=CC=C4)C5=CC=NC=C5)=C1SC6=NC=CC=C62 |
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