TH287

目录号: A15536

MTH1 inhibitor

TH287 Chemical Structure

CAS NO. 1609960-30-6

TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 2,500.00
50 mg
¥ 4,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16,
Targets
MTH1 (NUDT1)
0.8 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.16 mL 185.78 mL 371.57 mL
0.5 mM 7.43 mL 37.16 mL 74.31 mL
1 mM 3.72 mL 18.58 mL 37.16 mL
5 mM 0.74 mL 3.72 mL 7.43 mL

*The above data is based on the productmolecular weight 269.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15536
MECHANISM OF ACTION Inhibitor
M. Wt 269.13
Formula C11H10Cl2N4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1609960-30-6
Synonyms TH-287, TH 287
SMILES CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N

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