TH287
目录号: A15536
MTH1 抑制剂
TH287 是一种强效的 MTH1 (NUDT1) 抑制剂，其 IC50 值为 0.8 nM，对 MTH2, NUDT5, NUDT12, NUDT14, 和 NUDT16 的抑制作用较弱。
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生物活性
| Discription | TH287 is a potent inhibitor of MTH1 (NUDT1) with an IC50 value of 0.8 nM, less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16, | |||||
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产品信息
| 目录号 | A15536 |
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| 分子式 | C11H10Cl2N4 |
| 分子量 | 269.13 |
| CAS号 | 1609960-30-6 |
| SMILES | CNC1=NC(=NC(=C1)C2=C(C(=CC=C2)Cl)Cl)N |
| 其他名称 | TH-287, TH 287 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 48 mg/mL (178.35 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 9 mg/mL (33.44 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.16 mL | 185.78 mL | 371.57 mL |
| 0.5 mM | 7.43 mL | 37.16 mL | 74.31 mL |
| 1 mM | 3.72 mL | 18.58 mL | 37.16 mL |
| 5 mM | 0.74 mL | 3.72 mL | 7.43 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1609960-30-6 | 1609960-30-6 供应商 | 1609960-30-6 花费 | 1609960-30-6 生产商 | 订购 1609960-30-6 | 1609960-30-6 代理商