TH34
目录号: A19873
HDAC6/8/10 抑制剂
TH34 是一种 HDAC6/8/10 抑制剂,其半抑制浓度(IC50)分别为 4.6 微摩尔、1.9 微摩尔和 7.7 微摩尔,显示出对 HDAC1/2/3 的高选择性。
Discription | TH34, an HDAC6/8/10 inhibitor with IC50s of 4.6 μM, 1.9 μM, and 7.7 μM respectively, shows high selectivity over HDAC1/2/3. | ||
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Targets |
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目录号 | A19873 |
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分子式 | C15H16N2O2 |
分子量 | 256.3 |
CAS号 | 2196203-96-8 |
SMILES | O=C(NO)C1=CC=C(C)C(NCC2=CC=CC=C2)=C1 |
其他名称 | TH 34, TH-34 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 49 mg/mL (191.18 mM) | |
Water | Insoluble | ||
Ethanol | 14 mg/mL (54.62 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 39.02 mL | 195.08 mL | 390.17 mL |
0.5 mM | 7.8 mL | 39.02 mL | 78.03 mL |
1 mM | 3.9 mL | 19.51 mL | 39.02 mL |
5 mM | 0.78 mL | 3.9 mL | 7.8 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2