THAL-SNS-032

Name: THAL-SNS-032
SKU: A19088
Price: 770 CNY
Rating: 5 (288 reviews)

目录号: A19088

CDK9 degrader PROTAC

THAL-SNS-032 是一种选择性的 CDK9 降解剂 PROTAC，由与沙利度胺衍生物相连的 CDK结合剂 SNS-032 配体组成，该衍生物能够结合 E3 泛素连接酶小脑蛋白 (CRBN)。

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Grouped product items
规格	价格	库存
1mg	¥770.00	现货
5mg	¥1,960.00	现货
10mg	¥2,975.00	现货
25mg	¥4,795.00	现货
50mg	¥6,825.00	现货
100mg	¥9,275.00	现货
*10mM 1mL in DMSO**	¥2,975.00	现货
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Data Sheet

SDS

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生物活性

Discription

THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN).

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19088
分子式	C40H52N8O10S2
分子量	869.02
CAS号	2139287-33-3
SMILES	O=C(NCCOCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN4CCC(C(NC5=NC=C(SCC6=NC=C(C(C)(C)C)O6)S5)=O)CC4
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (102.41 mM)
	Water	Insoluble
	Ethanol	27 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.51 mL	57.54 mL	115.07 mL
0.5 mM	2.3 mL	11.51 mL	23.01 mL
1 mM	1.15 mL	5.75 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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