Thalidomide
目录号: A10924
E3 ubiquitin ligase 抑制剂
Thalidomide 可以直接抑制由 bFGF 或 VEGF 在体内诱导的血管生成。
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生物活性
| Discription | Thalidomide can directly inhibit angiogenesis induced by bFGF or VEGF in vivo. | |||||
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| Cell Research |
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产品信息
| 目录号 | A10924 |
|---|---|
| 分子式 | C13H10N2O4 |
| 分子量 | 258.23 |
| CAS号 | 50-35-1 |
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 48 mg/mL (185.87 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (7.74 mM) | ||
| In vivo | 5% DMSO+30% PEG 300+1% Tween 80+ddH2O (suspension) | 4 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 38.73 mL | 193.63 mL | 387.25 mL |
| 0.5 mM | 7.75 mL | 38.73 mL | 77.45 mL |
| 1 mM | 3.87 mL | 19.36 mL | 38.73 mL |
| 5 mM | 0.77 mL | 3.87 mL | 7.75 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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