Theralizumab (TGN1412) is a humanized IgG4 monoclonal antibody with superagonistic properties targeting CD28. It directly stimulates T-cell activation, which can lead to cytokine release syndrome (CRS). This antibody is primarily utilized in research focused on understanding and potentially treating rheumatoid arthritis.
Theralizumab (TGN1412) is a humanized IgG4 monoclonal antibody with superagonistic properties targeting CD28. It directly stimulates T-cell activation, which can lead to cytokine release syndrome (CRS). This antibody is primarily utilized in research focused on understanding and potentially treating rheumatoid arthritis.
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