Thiamet G
Thiamet G 是一种强效、选择性的 O-GlcNAcase 抑制剂，其抑制常数（Ki）为 21 nM，同时对人类溶酶体-己糖苷酶的选择性高达 37,000 倍。
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生物活性
| Discription | Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal-hexosaminidase. | ||
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产品信息
| 目录号 | A12895 |
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| 分子式 | C9H16N2O4S |
| 分子量 | 248.3 |
| CAS号 | 1009816-48-1 |
| SMILES | CCNC1=NC2C(C(C(OC2S1)CO)O)O |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 47 mg/mL (189.28 mM) | |
| Water | 47 mg/mL (189.28 mM) | ||
| Ethanol | 11 mg/mL (44.29 mM) | ||
| In vivo | Saline | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.27 mL | 201.37 mL | 402.74 mL |
| 0.5 mM | 8.05 mL | 40.27 mL | 80.55 mL |
| 1 mM | 4.03 mL | 20.14 mL | 40.27 mL |
| 5 mM | 0.81 mL | 4.03 mL | 8.05 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1009816-48-1 | 1009816-48-1 供应商 | 1009816-48-1 花费 | 1009816-48-1 生产商 | 订购 1009816-48-1 | 1009816-48-1 代理商