Thiostrepton

Name: Thiostrepton
SKU: A12890
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A12890

natural cyclic oligopeptide antibiotic

抗生素，能够抑制细菌蛋白质合成。通过GTP酶伸长因子G（EF-G）、EF-TU(GTP) 催化的aa-tRNA递送以及启动因子2（IF-2）的活性，抑制mRNA-tRNA转位。抗肿瘤剂；通过下调FOXM1表达，诱导乳腺癌细胞的细胞周期阻滞和凋亡。

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Grouped product items
规格	价格	库存
25mg	¥175.00	现货
50mg	¥210.00	现货
100mg	¥350.00	现货
250mg	¥805.00	现货
500mg	¥1,365.00	现货
1g	¥2,415.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

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生物活性

Discription	Antibiotic that inhibits bacterial protein synthesis. Inhibits mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery and the activity of initiation factor 2 (IF-2). Antitumor agent; induces cell cycle arrest and apoptosis in breast cancer cells via downregulation of FOXM1 expression.

产品信息

目录号	A12890
分子式	C72H85N19O18S5
分子量	1664.89
CAS号	1393-48-2
SMILES	CCC(C)C1C(=O)NC(C(=O)NC(=C)C(=O)NC(C(=O)NC23CCC(=NC2C4=CSC(=N4)C(C(OC(=O)C5=NC6=C(C=CC(C6O)N1)C(=C5)C(C)O)C)NC(=O)C7=CSC(=N7)C(NC(=O)C8CSC(=N8)/C(=C/C)/NC(=O)C(NC(=O)C9=CSC3=N9)C(C)O)C(C)(C(C)O)O)C1=NC(=CS1)C(=O)NC(=C)C(=O)NC(=C)C(=O)N)C)C
其他名称	a-8506
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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