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Thiostrepton

natural cyclic oligopeptide antibiotic

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产品目录号: A12890

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Thiostrepton 100mg A12890-100
¥ 600.00
Thiostrepton 250mg A12890-250
¥ 1,200.00
Thiostrepton 500mg A12890-500
¥ 2,000.00
Thiostrepton 1000mg A12890-1000
¥ 3,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Antibiotic that inhibits bacterial protein synthesis. Inhibits mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery and the activity of initiation factor 2 (IF-2). Antitumor agent; induces cell cycle arrest and apoptosis in breast cancer cells via downregulation of FOXM1 expression.

Thiostrepton

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Chemical Information

目录号 A12890
Mechanism of action N/A
分子量 1664.89
化学分子式 C72H85N19O18S5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1393-48-2
Synonyms a-8506
SMILES code CC[C@H](C)[C@@H]1C(=O)N[C@H](C(=O)NC(=C)C(=O)N[C@H](C(=O)N[C@]23CCC(=N[C@@H]2C4=CSC(=N4)[C@H]([C@H](OC(=O)C5=NC6=C(C=CC([C@@H]6O)N1)C(=C5)[C@H](C)O)C)NC(=O)C7=CSC(=N7)[C@@H](NC(=O)C8CSC(=N8)/C(=C/C)/NC(=O)[C@@H](NC(=O)C9=CSC3=N9)[C@@H](C)O)[C@@](C)([C@@H]
化学名称 N/A

生物活性

Description
Antibiotic that inhibits bacterial protein synthesis. Inhibits mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery and the activity of initiation factor 2 (IF-2). Antitumor agent; induces cell cycle arrest and apoptosis in breast cancer cells via downregulation of FOXM1 expression.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.01 mL 30.03 mL 60.06mL
0.5 mM 1.2 mL 6.01 mL 12.01 mL
1 mM 0.6 mL 3 mL 6.01 mL
5 mM 0.12 mL 0.6 mL 1.2 mL

*The above data is based on the productmolecular weight 1664.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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