THPP-1

Name: THPP-1
SKU: A22650
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A22650

PDE10A 抑制剂

THPP-1，一种SGC化学探针，是一种效力强大且口服生物利用度高的磷酸二酯酶10A（PDE10A）抑制剂，其对人类和大鼠PDE10A的Ki值分别为1 nM和1.3 nM。THPP-1在临床前物种中具有优异的药代动力学特性。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥1,050.00	现货
50mg	¥1,820.00	现货
100mg	¥2,730.00	现货
200mg	¥3,885.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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Data Sheet

SDS

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生物活性

Discription	THPP-1, a SGC chemical probe, is a potent and orally bioavailable phosphodiesterase 10A (PDE10A) inhibitor, with Ki values of 1 nM and 1.3 nM for human and rat PDE10A, respectively. THPP-1 has excellent pharmacokinetic properties in preclinical species.

产品信息

目录号	A22650
分子式	C23H21ClN6O3
分子量	464.9
CAS号	1257051-63-0
SMILES	O=C(C1=C2C=CC=CN2C=N1)N3CCC4=NC(C5=CC=C(N=C5)Cl)=NC(OCCOC)=C4C3
其他名称	THPP1,THPP 1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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