TIC10 isomer
目录号: A12720
AKT 抑制剂
TIC10 通过 Foxo3a 抑制 Akt 和 ERK 来诱导 TRAIL,具有优越的药物属性:能够穿越血脑屏障、具有更好的稳定性和改善的药代动力学。
AKT 抑制剂
Discription | TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. | ||
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Targets |
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目录号 | A12720 |
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分子式 | C24H26N4O |
分子量 | 386.5 |
CAS号 | 41276-02-2 |
SMILES | CC1=CC=CC=C1CN2C3=C(CN(CC3)CC4=CC=CC=C4)C(=O)N5C2=NCC5 |
其他名称 | TIC 10, TIC-10 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 11 mg/mL (28.46 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.87 mL | 129.37 mL | 258.73 mL |
0.5 mM | 5.17 mL | 25.87 mL | 51.75 mL |
1 mM | 2.59 mL | 12.94 mL | 25.87 mL |
5 mM | 0.52 mL | 2.59 mL | 5.17 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2