TIC10

Name: TIC10
SKU: A15903
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A15903

Akt 抑制剂

TIC10 通过 Foxo3a 抑制 Akt 和 ERK 来诱导 TRAIL，具有优越的药物属性：能够穿越血脑屏障、更高的稳定性和改善的药代动力学。处于第一/二阶段临床试验。

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Grouped product items
规格	价格	库存
5mg	¥315.00	现货
10mg	¥385.00	现货
25mg	¥595.00	现货
50mg	¥770.00	现货
100mg	¥1,225.00	现货
200mg	¥1,960.00	现货
500mg	¥3,360.00	现货
1g	¥4,795.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

TIC10 inactivates Akt and ERK to induce TRAIL through Foxo3a, possesses superior drug properties: delivery across the blood-brain barrier, superior stability and improved pharmacokinetics. Phase 1/2.

Targets

Target	Value

产品信息

目录号	A15903
分子式	C24H26N4O
分子量	386.49
CAS号	1616632-77-9
SMILES	CC1=CC=CC=C1CN(C2=NCCN32)C(C(C4)=C3CCN4CC5=CC=CC=C5)=O
其他名称	ONC-201
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 72 mg/mL (186.28 mM)
	Water	Insoluble
	Ethanol	Warmed: 72 mg/mL (186.28 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.87 mL	129.37 mL	258.74 mL
0.5 mM	5.17 mL	25.87 mL	51.75 mL
1 mM	2.59 mL	12.94 mL	25.87 mL
5 mM	0.52 mL	2.59 mL	5.17 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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