Ticagrelor (AZD6140)
            目录号: A11238
    
            P2Y12 拮抗剂
    
								
							Ticagrelor (AZD6140) 是首个可逆结合的口服 P2Y(12) 受体拮抗剂,能够阻断 ADP 引起的血小板聚集。
 
        | Discription | Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation. | |||||
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| Cell Research | 
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| 目录号 | A11238 | 
|---|---|
| 分子式 | C23H28F2N6O4S | 
| 分子量 | 522.6 | 
| CAS号 | 274693-27-5 | 
| SMILES | CCCSC1=NC2=C(C(=N1)N[C@@H]3C[C@H]3C4=CC(=C(C=C4)F)F)N=NN2[C@@H]5C[C@@H]([C@H]([C@H]5O)O)OCCO | 
| 其他名称 | AZD 6140 | 
| 储存条件 | Store lyophilized at -20ºC, keep desiccated.  | 
| In vitro (25°C) | DMSO | 99 mg/mL (189.45 mM) | |
| Water | Insoluble | ||
| Ethanol | 52 mg/mL (99.51 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 9 mg/mL | |
| *  <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg | 
|---|---|---|---|
| 0.1 mM | 19.14 mL | 95.68 mL | 191.35 mL | 
| 0.5 mM | 3.83 mL | 19.14 mL | 38.27 mL | 
| 1 mM | 1.91 mL | 9.57 mL | 19.14 mL | 
| 5 mM | 0.38 mL | 1.91 mL | 3.83 mL | 
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2