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Ticagrelor (AZD6140)

P2Y12 拮抗剂

158 Customer Reviews
产品目录号: A11238


产品名 目录号 价格 数量
Ticagrelor 50mg A11238-50
¥ 800.00
Ticagrelor 25mg A11238-25
¥ 500.00



Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation.

Ticagrelor (AZD6140)




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Chemical Information

目录号 A11238
Mechanism of action Antagonist
分子量 522.6
化学分子式 C23H28F2N6O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 274693-27-5
Synonyms AZD 6140
SMILES code CCCSC1=NC2=C(C(=N1)N[C@@H]3C[C@H]3C4=CC(=C(C=C4)F)F)N=NN2[C@@H]5C[C@@H]([C@H]([C@H]5O)O)OCCO
化学名称 (1S,2S,3R,5S)-3-[7-[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino]-5-(propylthio)- 3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol


Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation.


Solubility (25°C)* In vitro DMSO 105 mg/mL (200.93 mM)
Water <1 mg/mL (<1 mM)
Ethanol 53 mg/mL (101.42 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.14 mL 95.68 mL 191.35mL
0.5 mM 3.83 mL 19.14 mL 38.27 mL
1 mM 1.91 mL 9.57 mL 19.14 mL
5 mM 0.38 mL 1.91 mL 3.83 mL

*The above data is based on the productmolecular weight 522.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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