Tifcemalimab (JS004) is a humanized monoclonal antibody that targets BTLA (B and T lymphocyte attenuator), a key regulator in the immune checkpoint pathway. By binding specifically to BTLA, Tifcemalimab effectively inhibits the interaction between BTLA and its ligand HVEM, thereby blocking the BTLA-mediated inhibitory signaling pathway. This antibody is primarily utilized in cancer research to study the modulation of immune responses against tumor cells.
Tifcemalimab (JS004) is a humanized monoclonal antibody that targets BTLA (B and T lymphocyte attenuator), a key regulator in the immune checkpoint pathway. By binding specifically to BTLA, Tifcemalimab effectively inhibits the interaction between BTLA and its ligand HVEM, thereby blocking the BTLA-mediated inhibitory signaling pathway. This antibody is primarily utilized in cancer research to study the modulation of immune responses against tumor cells.
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