Tiplaxtinin (PAI-039)

目录号: A14190

PAI-1 inhbitor

Tiplaxtinin (PAI-039)

Tiplaxtinin (PAI-039) Chemical Structure

CAS NO. 393105-53-8

Tiplaxtinin (PAI-039)是一种纤溶酶原激活物抑制剂1(PAI-1)的选择性口服有效抑制剂,IC50为2.7μM。

库存: 现货

规格 价格 数量
5 mg
¥ 750.00
10 mg
¥ 850.00
25 mg
¥ 2,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Tiplaxtinin (PAI-039)是一种纤溶酶原激活物抑制剂1(PAI-1)的选择性口服有效抑制剂,IC50为2.7μM。
靶点信息
PAI-1
2.7 μM
In vitro (25°C) DMSO 62 mg/mL (141.1 mM)
Water Insoluble
Ethanol Warmed: 15 mg/mL (34.13 mM)
In vivo 2.0% Tween 80+0.5% methylcellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.76 mL 113.8 mL 227.59 mL
0.5 mM 4.55 mL 22.76 mL 45.52 mL
1 mM 2.28 mL 11.38 mL 22.76 mL
5 mM 0.46 mL 2.28 mL 4.55 mL

*The above data is based on the productmolecular weight 439.3833. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14190
作用机制 Inhibitor (抑制剂)
M. Wt 439.3833
Formula C24H16F3NO4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 393105-53-8
Synonyms PAI-039
SMILES C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O

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