Tiplaxtinin (PAI-039)

Name: Tiplaxtinin (PAI-039)
SKU: A14190
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A14190

PAI-1 inhbitor

1 篇发表文献

Tiplaxtinin 是一种选择性且口服有效的纤溶酶原激活物抑制剂-1 (PAI-1) 抑制剂，其 IC50 值为 2.7 微摩尔。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥350.00	现货
10mg	¥560.00	现货
25mg	¥1,050.00	现货
50mg	¥1,855.00	现货
100mg	¥3,570.00	现货
500mg	¥8,015.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Tiplaxtinin (PAI-039)发表的1篇文献

Saijo A, .et al. , Cancer Lett, 2018, May 1;421:17-27 PMID: 29448000

生物活性

Discription

Tiplaxtinin is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 μM.

Targets

Target	Value

产品信息

目录号	A14190
分子式	C24H16F3NO4
分子量	439.3833
CAS号	393105-53-8
SMILES	C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O
其他名称	PAI-039
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	62 mg/mL (141.1 mM)
	Water	Insoluble
	Ethanol	Warmed: 15 mg/mL (34.13 mM)
In vivo	2.0% Tween 80+0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.76 mL	113.8 mL	227.59 mL
0.5 mM	4.55 mL	22.76 mL	45.52 mL
1 mM	2.28 mL	11.38 mL	22.76 mL
5 mM	0.46 mL	2.28 mL	4.55 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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