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Tirabrutinib hydrochloride

目录号: A22375
BTK 抑制剂
Tirabrutinib(ONO-4059)盐酸盐是一种选择性的新型BTK抑制剂,其IC50为2.2纳摩尔。Tirabrutinib通过与B细胞内的BTK结合,从而阻断B细胞受体信号传导并阻碍B细胞的发展。
Grouped product items
规格 价格 库存 数量
2mg
¥175.00
现货
5mg
¥245.00
现货
10mg
¥455.00
现货
25mg
¥840.00
现货
50mg
¥1,400.00
现货
100mg
¥2,520.00
现货
10mM * 1mL in DMSO
¥280.00
现货
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生物活性
Discription Tirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development.
产品信息
目录号 A22375
分子式 C25H23ClN6O3
分子量 490.94
CAS号 1439901-97-9
SMILES O=C1N(C2=CC=C(OC3=CC=CC=C3)C=C2)C4=C(N)N=CN=C4N1[C@H]5CN(C(C#CC)=O)CC5.[H]Cl
其他名称 ONO-4059 hydrochloride, GS-4059 hydrochloride
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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