Tirabrutinib hydrochloride
目录号: A22375
BTK 抑制剂
Tirabrutinib(ONO-4059)盐酸盐是一种选择性的新型BTK抑制剂,其IC50为2.2纳摩尔。Tirabrutinib通过与B细胞内的BTK结合,从而阻断B细胞受体信号传导并阻碍B细胞的发展。
Discription | Tirabrutinib (ONO-4059) hydrochloride is a selective and novel inhibitor of BTK with IC50 2.2 nm, Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor signaling and impeding B-cell development. |
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目录号 | A22375 |
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分子式 | C25H23ClN6O3 |
分子量 | 490.94 |
CAS号 | 1439901-97-9 |
SMILES | O=C1N(C2=CC=C(OC3=CC=CC=C3)C=C2)C4=C(N)N=CN=C4N1[C@H]5CN(C(C#CC)=O)CC5.[H]Cl |
其他名称 | ONO-4059 hydrochloride, GS-4059 hydrochloride |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2