TMP 269

目录号: A14128

HDAC inhibitor

TMP 269

TMP 269 Chemical Structure

CAS NO. 1314890-29-3

TMP 269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,500.00
25 mg
¥ 2,500.00
10mM * 1mL in DMSO
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

TMP 269 is a potent, selective class IIa HDAC inhibitor with IC50 of 157 nM, 97 nM, 43 nM and 23 nM for HDAC4, HDAC5, HDAC7 and HDAC9, respectively.
In vitro DMSO 100 mg/mL (194.35 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL heating (3.88 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.44 mL 97.18 mL 194.36 mL
0.5 mM 3.89 mL 19.44 mL 38.87 mL
1 mM 1.94 mL 9.72 mL 19.44 mL
5 mM 0.39 mL 1.94 mL 3.89 mL

*The above data is based on the productmolecular weight 514.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A14128
MECHANISM OF ACTION Inhibitor
M. Wt 514.52
Formula C25H21F3N4O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1314890-29-3
Synonyms TMP-269,TMP269
SMILES O=C(c1cccc(c1)c1noc(n1)C(F)(F)F)NCC1(CCOCC1)c1scc(n1)c1ccccc1

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