TNKS-IN-4 is a potent tankyrase (TNKS) inhibitor, exhibiting IC50 values of 0.1 nM for TNKS1 and 7.6 nM for TNKS2. This compound plays a critical role in the modulation of Wnt signaling pathways and has been leveraged in research focused on APC-mutant colorectal cancer. TNKS-IN-4 facilitates investigations into tumorigenesis and provides insights into therapeutic strategies targeting tankyrase activity.
TNKS-IN-4 is a potent tankyrase (TNKS) inhibitor, exhibiting IC50 values of 0.1 nM for TNKS1 and 7.6 nM for TNKS2. This compound plays a critical role in the modulation of Wnt signaling pathways and has been leveraged in research focused on APC-mutant colorectal cancer. TNKS-IN-4 facilitates investigations into tumorigenesis and provides insights into therapeutic strategies targeting tankyrase activity.
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