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TNP 470是富马西林的类似物，在体外显示有效的抗血管生成活性。已显示出抑制MetAP-2（甲硫氨酸氨基肽酶II型）的作用。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.88 mL | 124.42 mL | 248.83 mL |
| 0.5 mM | 4.98 mL | 24.88 mL | 49.77 mL |
| 1 mM | 2.49 mL | 12.44 mL | 24.88 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.98 mL |
*The above data is based on the productmolecular weight 401.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14014 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 401.88 |
| Formula | C19H28CINO6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 129298-91-5 |
| Synonyms | TNP470, TNP 470, O-(Chloroacetyl-carbamoyl) Fumagillol, NSC 642492, AGM-1470 |
| SMILES | CC(=CC[C@H]1[C@](O1)(C)C2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)NC(=O)CCl)OC)C |
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