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Toceranib (PHA 291639, SU 11654)

促销

c-Kit, PDGFR, VEGFR 抑制剂

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产品目录号: A11581

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Toceranib (PHA 291639, SU 11654) 5mg A11581-5
¥ 900.00
Toceranib (PHA 291639, SU 11654) 10mg A11581-10
¥ 1,600.00
Toceranib (PHA 291639, SU 11654) 25mg A11581-25
¥ 2,800.00
Toceranib (PHA 291639, SU 11654) 50mg A11581-50
¥ 4,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.

Toceranib (PHA 291639, SU 11654)

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Toceranib (PHA 291639, SU 11654) 发表的文献 (1)
  • Masaya Igase, .et al. Oncolytic reovirus synergizes with chemotherapeutic agents to promote cell death in canine mammary gland tumor, Can J Vet Res, 2016, Jan; 80(1): 21每31 PMID: 26733729

Chemical Information

目录号 A11581
Mechanism of action Inhibitor
分子量 396.46
化学分子式 C22H25FN4O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 356068-94-5
Synonyms PHA 291639, SU 11654, PHA-291639, SU-11654, PHA291639, SU11654
SMILES code CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O
化学名称 5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-1H-pyrrole-3-carboxamide

生物活性

Description
Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.22 mL 126.12 mL 252.23mL
0.5 mM 5.04 mL 25.22 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL

*The above data is based on the productmolecular weight 396.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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