TOK-001 (Galeterone)

Name: TOK-001 (Galeterone)
SKU: A11138

目录号: A11138

CYP17 抑制剂

TOK-001 (Galeterone) Chemical Structure

CAS NO. 851983-85-2

TOK-001 (Galeterone)既是雄激素受体拮抗剂又是CYP17A1抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 550.00
10 mg	￥ 800.00
50 mg	￥ 2,450.00
100 mg	￥ 4,050.00
10mM * 1mL in DMSO	￥ 550.00

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生物活性

TOK-001 (Galeterone)既是雄激素受体拮抗剂又是CYP17A1抑制剂。

靶点信息

CYP17	Androgen Receptor
300 nM	384 nM

溶解度 *

In vitro (25°C)	DMSO	21 mg/mL (54.04 mM)
	Water	Insoluble
	Ethanol	Warmed: 36 mg/mL (92.65 mM)
In vivo	0.5% hydroxyethyl cellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.75 mL	128.77 mL	257.53 mL
0.5 mM	5.15 mL	25.75 mL	51.51 mL
1 mM	2.58 mL	12.88 mL	25.75 mL
5 mM	0.52 mL	2.58 mL	5.15 mL

*The above data is based on the productmolecular weight 388.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11138
作用机制	Inhibitor (抑制剂)
M. Wt	388.3
Formula	C26H32N2O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	851983-85-2
Synonyms	VN/124-1
SMILES	C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4N5C=NC6=CC=CC=C65)C)O