TOK-001 (Galeterone)
目录号: A11138
CYP17 抑制剂
TOK-001(Galeterone)既是一种雄激素受体拮抗剂,也是一种CYP17A1抑制剂。
| Discription | TOK-001 (Galeterone) is both an androgen receptor antagonist and CYP17A1 inhibitor. | |||||
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| Cell Research |
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| 目录号 | A11138 |
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| 分子式 | C26H32N2O |
| 分子量 | 388.3 |
| CAS号 | 851983-85-2 |
| SMILES | C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4N5C=NC6=CC=CC=C65)C)O |
| 其他名称 | VN/124-1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 21 mg/mL (54.04 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 36 mg/mL (92.65 mM) | ||
| In vivo | 0.5% hydroxyethyl cellulose | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.75 mL | 128.77 mL | 257.53 mL |
| 0.5 mM | 5.15 mL | 25.75 mL | 51.51 mL |
| 1 mM | 2.58 mL | 12.88 mL | 25.75 mL |
| 5 mM | 0.52 mL | 2.58 mL | 5.15 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2