Toll-Like Receptor 7 Ligand II is a cell-permeable hydroxyadenine compound which acts as a potent and highly specific TLR7 (toll-like receptor 7) agonist without any detectable activity towards TLR2/3/5/8/9. It is shown to be 10-times more potent than R848 in stimulating the production of TLR7-dependent cytokines in cultures in vitro .
Cell Research
Cell Line
Type
Value
Description
References
产品信息
目录号
A12683
分子式
C15H17N5O3
分子量
315.33
CAS号
226907-52-4
SMILES
COCCOC1=NC2=C(C(=N1)N)NC(=O)N2CC3=CC=CC=C3
其他名称
CL087; SM360320
储存条件
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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