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Toll-Like Receptor 7 Ligand II

TLR7 Ligand

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产品目录号: A12683

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Toll-Like Receptor 7 Ligand II 5mg A12683-5
¥ 3,500.00
Toll-Like Receptor 7 Ligand II 10mg A12683-10
¥ 6,500.00
Toll-Like Receptor 7 Ligand II 25mg A12683-25
¥ 12,000.00
Toll-Like Receptor 7 Ligand II 50mg A12683-50
¥ 20,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Toll-Like Receptor 7 Ligand II is a cell-permeable hydroxyadenine compound which acts as a potent and highly specific TLR7 (toll-like receptor 7) agonist without any detectable activity towards TLR2/3/5/8/9. It is shown to be 10-times more potent than R848 in stimulating the production of TLR7-dependent cytokines in cultures in vitro .

Toll-Like Receptor 7 Ligand II

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Chemical Information

目录号 A12683
Mechanism of action N/A
分子量 315.33
化学分子式 C15H17N5O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 226907-52-4
Synonyms CL087; SM360320
SMILES code COCCOC1=NC2=C(C(=N1)N)NC(=O)N2CC3=CC=CC=C3
化学名称 6-Amino-7,9-dihydro-2-(2-methoxyethoxy)-9-(phenylmethyl)-8H-purin-8-one

生物活性

Description
Toll-Like Receptor 7 Ligand II is a cell-permeable hydroxyadenine compound which acts as a potent and highly specific TLR7 (toll-like receptor 7) agonist without any detectable activity towards TLR2/3/5/8/9. It is shown to be 10-times more potent than R848 in stimulating the production of TLR7-dependent cytokines in cultures in vitro .

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.71 mL 158.56 mL 317.13mL
0.5 mM 6.34 mL 31.71 mL 63.43 mL
1 mM 3.17 mL 15.86 mL 31.71 mL
5 mM 0.63 mL 3.17 mL 6.34 mL

*The above data is based on the productmolecular weight 315.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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