Tolnaftate
目录号: A11657
托娜夫特是一种合成硫代氨基甲酸盐，用作抗真菌剂。它被认为可以抑制角鲨烯环氧化酶，这是麦角甾醇（真菌膜的关键成分）生物合成途径中的一个重要酶，其作用方式与烯丙胺类似。
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生物活性
| Discription | Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. It is believed to inhibit the squalene epoxidase, an important enzyme in the biosynthetic pathway of ergosterol (a key component of the fungal membrane) in a similar way to allylamines. |
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产品信息
| 目录号 | A11657 |
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| 分子式 | C19H17NOS |
| 分子量 | 307.41 |
| CAS号 | 2398-96-1 |
| SMILES | CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 56 mg/mL (182.16 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.53 mL | 162.65 mL | 325.3 mL |
| 0.5 mM | 6.51 mL | 32.53 mL | 65.06 mL |
| 1 mM | 3.25 mL | 16.26 mL | 32.53 mL |
| 5 mM | 0.65 mL | 3.25 mL | 6.51 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 2398-96-1 | 2398-96-1 供应商 | 2398-96-1 花费 | 2398-96-1 生产商 | 订购 2398-96-1 | 2398-96-1 代理商