Tolvaptan

Name: Tolvaptan
SKU: A11594

目录号: A11594

vasopressin receptor 2 拮抗剂

Tolvaptan Chemical Structure

CAS NO. 150683-30-0

Tolvaptan是一种选择性的竞争性精氨酸加压素受体2拮抗剂，IC50为1.28μM。

库存：现货

规格	价格	数量
5 mg	￥ 700.00
10 mg	￥ 1,200.00
25 mg	￥ 2,400.00
50 mg	￥ 3,800.00
10mM * 1mL in DMSO	￥ 1,200.00

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生物活性

Tolvaptan是一种选择性的竞争性精氨酸加压素受体2拮抗剂，IC50为1.28μM。

靶点信息

vasopressin receptor 2	vasopressin receptor 1a
3 nM	580 nM

溶解度 *

In vitro	DMSO	81 mg/mL (180.42 mM)
	Water	Insoluble
	Ethanol	5 mg/mL (11.13 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.27 mL	111.37 mL	222.75 mL
0.5 mM	4.45 mL	22.27 mL	44.55 mL
1 mM	2.23 mL	11.14 mL	22.27 mL
5 mM	0.45 mL	2.23 mL	4.45 mL

*The above data is based on the productmolecular weight 448.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11594
作用机制	Antagonist (拮抗剂)
M. Wt	448.94
Formula	C26H25ClN2O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	150683-30-0
SMILES	CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C