Tolvaptan
目录号: A11594
vasopressin receptor 2 拮抗剂
Tolvaptan 是一种选择性、竞争性的精氨酸加压素受体2拮抗剂，其 IC50 为 1.28μM。
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生物活性
| Discription | Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM. | ||
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| Targets |
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产品信息
| 目录号 | A11594 |
|---|---|
| 分子式 | C26H25ClN2O3 |
| 分子量 | 448.94 |
| CAS号 | 150683-30-0 |
| SMILES | CC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)C(=O)N3CCCC(C4=C3C=CC(=C4)Cl)O)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 81 mg/mL (180.42 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (11.13 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.27 mL | 111.37 mL | 222.75 mL |
| 0.5 mM | 4.45 mL | 22.27 mL | 44.55 mL |
| 1 mM | 2.23 mL | 11.14 mL | 22.27 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.45 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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