Tomivosertib

Name: Tomivosertib
SKU: A20407
Price: 315 CNY
Rating: 5 (288 reviews)

目录号: A20407

MNK1/MNK2 抑制剂

Tomivosertib（eFT508）是一种效力强大、高度选择性且口服生物利用度高的 MNK1 和 MNK2 抑制剂，对这两种亚型的 IC50 值为 1-2 nM。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
5mg	¥1,050.00	现货
10mg	¥1,645.00	现货
25mg	¥3,290.00	现货
50mg	¥4,795.00	现货
100mg	¥6,825.00	现货
*10mM 1mL in DMSO**	¥1,260.00	现货
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Data Sheet

SDS

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生物活性

Discription

Tomivosertib (eFT508) is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20407
分子式	C17H20N6O2
分子量	340.38
CAS号	1849590-01-7
SMILES	O=C(C1=C(C)C=C(NC2=NC=NC(N)=C2)C(N13)=O)NC43CCCCC4
其他名称	eFT508, eFT 508, eFT-508
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	12 mg/mL (35.25 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.38 mL	146.89 mL	293.79 mL
0.5 mM	5.88 mL	29.38 mL	58.76 mL
1 mM	2.94 mL	14.69 mL	29.38 mL
5 mM	0.59 mL	2.94 mL	5.88 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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