Tonapofylline

Name: Tonapofylline
SKU: A21328
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A21328

adenosine A1 receptor 拮抗剂

Tonapofylline (BG 9928) 是一种口服活性且选择性的腺苷A1受体拮抗剂，对人类腺苷A1受体（hA1）的Ki值为7.4 nM，相较于人类腺苷A2A受体具有915倍的选择性，与人类腺苷A2B受体具有12倍的选择性，目前正在开发中，用于治疗心力衰竭。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥560.00	现货
10mg	¥945.00	现货
25mg	¥1,960.00	现货
50mg	¥2,835.00	现货
100mg	¥4,060.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription	Tonapofylline (BG 9928) is an orally active and selective adenosine A1 receptor antagonist with a Ki of 7.4 nM for human adenosine A1 receptor (hA1), which displays 915-fold selectivity versus human adenosine A2A receptor and 12-fold selectivity versus human adenosine A2B receptor and is used in development for the treatment of heart failure.

产品信息

目录号	A21328
分子式	C22H32N4O4
分子量	416.51
CAS号	340021-17-2
SMILES	O=C(O)CCC1(CC2)CCC2(C(N3)=NC(N(CCC)C(N4CCC)=O)=C3C4=O)CC1
其他名称	BG 9928
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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