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Topotecan HCl (Hycamtin)


DNA topoisomerase I 抑制剂

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产品目录号: A10939


产品名 目录号 价格 数量
Topotecan HCl 50mg A10939-50
¥ 1,500.00
Topotecan HCl 100mg A10939-100
¥ 2,500.00
Topotecan HCl 200mg A10939-200
¥ 4,200.00
Topotecan HCl (Hycamtin) 10mM * 1mL in DMSO A10939-10mM-D
¥ 730.00



Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.

Topotecan HCl (Hycamtin)




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Chemical Information

目录号 A10939
Mechanism of action Inhibitor
分子量 457.9
化学分子式 C23H23N3O5 .HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 119413-54-6
Synonyms Hycamtin
SMILES code CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl
化学名称 (S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride


Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.


Solubility (25°C) * In vitro DMSO 92 mg/mL (200.91 mM)
Water 92 mg/mL (200.91 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.84 mL 109.19 mL 218.39mL
0.5 mM 4.37 mL 21.84 mL 43.68 mL
1 mM 2.18 mL 10.92 mL 21.84 mL
5 mM 0.44 mL 2.18 mL 4.37 mL

*The above data is based on the productmolecular weight 457.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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