Toralizumab (IDEC-131) is a humanized monoclonal antibody targeting CD40 ligand (CD154), composed of human gamma 1 heavy chains and kappa light chains. This antibody selectively binds to CD40L expressed on T cells, effectively inhibiting CD40-mediated signaling. As an immunosuppressive agent, Toralizumab is primarily investigated for its therapeutic potential in systemic lupus erythematosus (SLE) research.
Toralizumab (IDEC-131) is a humanized monoclonal antibody targeting CD40 ligand (CD154), composed of human gamma 1 heavy chains and kappa light chains. This antibody selectively binds to CD40L expressed on T cells, effectively inhibiting CD40-mediated signaling. As an immunosuppressive agent, Toralizumab is primarily investigated for its therapeutic potential in systemic lupus erythematosus (SLE) research.
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