TP-3654
目录号: A20584
Pim kinase 抑制剂
TP-3654 是第二代 Pim 激酶抑制剂,其对 Pim-1 和 Pim-3 的 Ki 值分别为 5 nM 和 42 nM。
Discription | TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively. |
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目录号 | A20584 |
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分子式 | C22H25F3N4O |
分子量 | 418.46 |
CAS号 | 1361951-15-6 |
SMILES | OC(C)(C)[C@H]1CC[C@H](NC2=NN3C(C=C2)=NC=C3C4=CC=CC(C(F)(F)F)=C4)CC1 |
其他名称 | TP3654, TP 3654 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 71 mg/mL (169.66 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (11.94 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.9 mL | 119.49 mL | 238.97 mL |
0.5 mM | 4.78 mL | 23.9 mL | 47.79 mL |
1 mM | 2.39 mL | 11.95 mL | 23.9 mL |
5 mM | 0.48 mL | 2.39 mL | 4.78 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2