Trametinib (DMSO solvate)

Name: Trametinib (DMSO solvate)
SKU: A21450
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A21450

MEK 抑制剂

1 篇发表文献

Trametinib DMSO solvate (GSK-1120212 (DMSO solvate); JTP-74057 (DMSO solvate)) 是一种强效的 MEK 抑制剂，专门抑制 MEK1/2，其 IC50 值约为 2 nM。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥315.00	现货
50mg	¥350.00	现货
100mg	¥525.00	现货
200mg	¥770.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Trametinib (DMSO solvate)发表的1篇文献

Yuki Shimizu, .et al. , Cancer Lett, 2022, Sep 1;543 PMID: 35724767

生物活性

Discription

Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is a potent MEK inhibitor that specifically inhibits MEK1/2, with an IC50 value of about 2 nM.

Targets

Target	Value

产品信息

目录号	A21450
分子式	C28H29FIN5O5S
分子量	693.53
CAS号	1187431-43-1
SMILES	CN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O
其他名称	GSK-1120212 (DMSO solvate), GSK1120212, GSK 1120212; JTP-74057 (DMSO solvate), JTP74057, JTP 74057
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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