Trametinib (DMSO solvate)

目录号: A21450

MEK inhibitor

Trametinib (DMSO solvate)

Trametinib (DMSO solvate) Chemical Structure

CAS NO. 1187431-43-1

Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is a potent MEK inhibitor that specifically inhibits MEK1/2, with an IC50 value of about 2 nM.

库存: 现货

规格 价格 数量
10 mg
¥ 540.00
25 mg
¥ 1,080.00
50 mg
¥ 1,860.00
100 mg
¥ 3,180.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Trametinib DMSO solvate (GSK-1120212 (DMSO solvate);JTP-74057 (DMSO solvate)) is a potent MEK inhibitor that specifically inhibits MEK1/2, with an IC50 value of about 2 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.42 mL 72.09 mL 144.19 mL
0.5 mM 2.88 mL 14.42 mL 28.84 mL
1 mM 1.44 mL 7.21 mL 14.42 mL
5 mM 0.29 mL 1.44 mL 2.88 mL

*The above data is based on the productmolecular weight 693.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21450
作用机制 Inhibitor (抑制剂)
M. Wt 693.53
Formula C28H29FIN5O5S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1187431-43-1
Synonyms GSK-1120212 (DMSO solvate), GSK1120212, GSK 1120212; JTP-74057 (DMSO solvate), JTP74057, JTP 74057
SMILES CN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O

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