Trans-Tranilast
目录号: A17790
Tranilast 是一种抑制内皮细胞中白细胞介素-6产生的抑制剂。它通过减少成纤维细胞中的胶原蛋白合成和抑制神经纤维瘤细胞的生长来发挥作用。
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生物活性
| Discription | Tranilast is an inhibitor of the production of interleukin-6 in endothelial cells. It acts by reducing collagen synthesis in fibroblasts and inhibiting growth of neurofibroma cells. |
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产品信息
| 目录号 | A17790 |
|---|---|
| 分子式 | C18H17NO5 |
| 分子量 | 327.33 |
| CAS号 | 70806-55-2 |
| SMILES | O=C(O)C1=CC=CC=C1NC(/C=C/C2=CC=C(OC)C(OC)=C2)=O |
| 其他名称 | Tranilast; Rizaben; SB-252218; SB 252218; SB252218; |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 62 mg/mL (189.41 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL (12.22 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.55 mL | 152.75 mL | 305.5 mL |
| 0.5 mM | 6.11 mL | 30.55 mL | 61.1 mL |
| 1 mM | 3.06 mL | 15.28 mL | 30.55 mL |
| 5 mM | 0.61 mL | 3.06 mL | 6.11 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 70806-55-2 | 70806-55-2 供应商 | 70806-55-2 花费 | 70806-55-2 生产商 | 订购 70806-55-2 | 70806-55-2 代理商