TRi-1
目录号: A18556
TXNRD1 抑制剂
TRi-1 是一种强效、特异性且不可逆的细胞质硫氧还蛋白还原酶1（TXNRD1）抑制剂，其半抑制浓度（IC50）为12纳摩尔。TRi-1 对于抗癌治疗具有很小的线粒体毒性。
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生物活性
| Discription | TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy. |
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产品信息
| 目录号 | A18556 |
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| 分子式 | C12H9ClN2O5S |
| 分子量 | 328.73 |
| CAS号 | 246020-68-8 |
| SMILES | O=[N+](C1=CC=C(OC)N=C1S(=O)(C2=CC=C(Cl)C=C2)=O)[O-] |
| 其他名称 | TRi1 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 25 mg/mL (76.04 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.42 mL | 152.1 mL | 304.2 mL |
| 0.5 mM | 6.08 mL | 30.42 mL | 60.84 mL |
| 1 mM | 3.04 mL | 15.21 mL | 30.42 mL |
| 5 mM | 0.61 mL | 3.04 mL | 6.08 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 246020-68-8 | 246020-68-8 供应商 | 246020-68-8 花费 | 246020-68-8 生产商 | 订购 246020-68-8 | 246020-68-8 代理商